AAT Administrative Appeals Tribunal
ABN Australian Business Number
ACC American Chemistry Council
ACCC Australian Competition and Consumer Commission
ACCS Advisory Committee on Chemicals Scheduling
Act, the Commonwealth Industrial Chemicals (Notification and Assessment) Act 1989
ACToRAggregated Computational Toxicology Resource (US)
ADGC Australian Dangerous Goods Code—the Australian Code for the Transport of Dangerous Goods by Road and Rail
ADI acceptable daily intake
ADR adverse drug reaction
AGD anogenital distance; Attorney-General's Department
AGI anogenital index
AgVet agricultural and veterinary (chemical) 
ai active ingredient
AICS Australian Inventory of Chemical Substances
ANAO Australian National Audit Office
APHA American Public Health Association
APVMA Australian Pesticides and Veterinary Medicines Authority
ArticleAn object that:
  • is manufactured for use for a particular purpose, being a purpose that requires that the object have a particular shape, surface or design, and
  • is formed to that shape, surface or design during manufacture, and
  • undergoes no change of chemical composition when used for that purpose except as an intrinsic aspect of that use ,
but does not include a particle or a fluid.
AS Australian Standard
ASCC Australian Safety and Compensation Council (previously National Occupational Health and Safety Commission - NOHSC); ow: Safe Work Australia
ATSDRAgency for Toxic Substances and Disease Registry (US)
B bioaccumulative
BAF bioaccumulation factor
Basic informationIn relation to a chemical, means all of the following:
  • name or names by which the chemical is known to the public or is intended by its importer or manufacturer to be so known,
  • general (common) uses of the chemical,
  • precautions and restrictions to be observed in manufacturing, handling, storing, using and disposing of the chemical,
  • recommendations arising from the assessment of the chemical under the Act relating to disposing of the chemical and rendering it harmless,
  • procedures to be followed in the event of an emergency involving the chemical,
  • prescribed physical and chemical data about the chemical, not being data that would reveal the chemical's composition (Regulation 3),
  • prescribed data relating to the health effects or environmental effects of the chemical (Regulation 4).
BCF bioconcentration factor
BCFCORRECTED calculated bioconcentration factor corrected for mitigating factors
BCFMAX calculated maximum bioconcentration factor
Biological material Any matter derived from or constituting a living organism, except a whole animal or a whole plant.
  • a polymer directly produced by living or once-living cells or cellular components, or
  • synthetic equivalent of such a polymer, or
  • derivative or modification of such a polymer in which the original polymer remains substantially intact.
Blend To mix or combine ingredients in such a way that does not result in the creation or synthesis of a chemical
BMF biomagnification factor
BOD biochemical (biological) oxygen demand
bw body weight
calc. calculated
CAS Chemical Abstracts Service
CAS RN Chemical Abstracts Service Registry Number
CDC Centers for Disease Control and Prevention
CEC Commercial Evaluation Category Permit for new chemicals (NICNAS)
cf. confer, compare
CFRCode of Federal Regulations (US)
CHMS Canadian Health Measures Survey
CHNC Clearing House on New Chemicals (OECD) 
CHOChinese hamster ovary
CICAD Concise International Chemical Assessment Document 
CIR Cosmetic Ingredient Review
COAG Council of Australian Governments
CoCAM Cooperative Chemicals Assessment Meeting
CoCAP Cooperative Chemicals Assessment Program
COLIPA European Cosmetic Toiletry and Perfumery Association (Cosmetics Europe)
conc. concentration
CosIng Cosmetic Ingredient and Substances Database
CPI cell proliferation index
CPSC Consumer Products Safety Commission
CRIS Cost Recovery Implementation Statement 
CSTEE Scientific Committee on Toxicity, Ecotoxicity and the Environment
d day
Da Daltons (units of molecular weight)
Dangerous goods Substances or articles that, because of their physical, chemical (physicochemical) or acute toxicity properties, present immediate hazard to people, property or the environment. Types of substances classified as dangerous goods include explosives, flammable liquids and gases, corrosives, chemically reactive or acutely (highly) toxic substances. Dangerous goods are also defined as substances that fall within the Australian Dangerous Goods Code.
DBP dibutyl phthalate, di-n-butyl phthalate 
DecaBDE  decabromodiphenyl ether  
DEHP diethylhexyl phthalate 
DEP diethyl phthalate 
DIBP  diisobutyl phthalate 
DIDP diisodecyl phthalate 
DIIS Australian Government Department of Industry, Innovation and Science
DINP diisononyl phthalate 
DMEP bis (2-methoxyethyl) phthalate 
DMP dimethyl phthalate 
DNA deoxyribonucleic acid
DnOP di-n-octyl phthalate 
DOC dissolved organic carbon 
DoH Australian Government Department of Health
DOL dissolved oxygen level 
DSL Domestic Substances List (Canada)
ECEuropean Commission
EC3 estimated concentration needed to produce a three-fold increase in lymphocyte proliferation
EC50 or EC50 median effective concentration or half maximal effective concentration
ECB European Chemicals Bureau
ECETOC European Centre for Ecotoxicology and Toxicology of Chemicals
ECHA European Chemicals Agency
ECOSAR ECOlogical Structure Activity Relationships
ECx effective concentration for x% of the test population
e.g. exempli gratia, for example
EHD estimated human dose
EIP Early Introduction Permit for new chemicals (NICNAS)
EL50 / EL50  effective loading rate resulting in 50% effect 
End useThe purpose to which an industrial chemical is applied. For example: coatings and paints, inks and toners, cosmetic.
Environment Australian Government Department of the Environment
EOP Controlled Use (Export Only) Permit for new chemicals (NICNAS)
EP European Pharmacopoeia (also known as PH. Eur.) 
EPHC Environment Protection and Heritage Council
ErC50 or ErC50EC50 (see above) in terms of reduction of growth rate
ESD ecologically sustainable development 
ESIS European chemical Substances Information System
et al. et alii, and others
etc. et cetera, and so forth, and so on
EUEuropean Union
EU RAREuropean Union Risk Assessment Report
Excluded use In relation to a chemical, means:
  • use as an agricultural chemical or a constituent of an agricultural chemical, or
  • use as a veterinary chemical or a constituent of a veterinary chemical, or
  • therapeutic use or use as an ingredient or component in the preparation or manufacture of goods for therapeutic use, or
  • use as food intended for consumption by humans or animals or a constituent of such food, or
  • use as a food additive in food referred to in Subsection 7(2) of the ICNA Act.
Existing chemicalAn industrial chemical not defined as a new chemical. This includes naturally occurring chemicals. Existing chemicals are those listed on the AICS.
F0 parental generation
F1 first filial/offspring generation
F2 second filial/offspring generation
FAO (UN) Food and Agriculture Organisation (of the United Nations) 
FAQ frequently asked question/s
FDA Food and Drug Administration (United States)
FGEW functional group equivalent weight
FSANZ Food Standards Australia New Zealand
FTIR Fourier transform infrared spectroscopy
g gram
g/molgrams per mole
GC gas chromatography
GD gestational day
GHS Globally Harmonised System of Classification and Labelling of Chemicals (United Nations)
GI gastrointestinal
GLP good laboratory practice
GM genetically modified
GMPgood manufacturing practice
GPMTGuinea pig maximisation test
GWP global warming potential
h or hr hour
hazard inherent property of an agent or situation having the potential to cause adverse effects when an organism, system or (sub)population is exposed to that agent; intrinsic property of a substance to cause harm
Hazardous chemical One that, following worker exposure, can have an adverse effect on health. Examples of hazardous chemicals include poisons, substances that cause burns or skin and eye irritation, and substances that may cause cancer. Many hazardous chemicals are also classed as dangerous goods. A substance is deemed to be hazardous if it satisfies the criteria for a hazard class in the UN's Globally Harmonised System of Classification and Labelling of Chemicals, 3rd edition (GHS), but does not include a chemical that satisfies the criteria solely for one of the following hazard classes:
  1. flammable gases, category 2
  2. acute toxicity—oral, category 5
  3. acute toxicity—dermal, category 5
  4. acute toxicity—inhalation, category 5
  5. skin corrosion/irritation, category 3
  6. serious eye damage/eye irritation, category 2B
  7. aspiration hazard, category 2
  8. hazardous to the aquatic environment, category acute 1, 2 or 3
  9. hazardous to the aquatic environment, category chronic 1, 2, 3 or 4
  10. hazardous to the ozone layer.
Note: The GHS has been adopted in the Work Health and Safety legislation of many jurisdictions, with more to follow. A five-year transition period (up until 31 December 2016) will apply in which classifications under the Approved Criteria will be acceptable if classification under the GHS is not available to the notifier. To assist in classification, Safe Work Australia maintains the Hazardous Substances Information System, an online database containing classification information for hazardous substances that have been classified in accordance with the approved criteria. However, the database is not a comprehensive source of classification information for workplace substances.
Hb haemoglobin
HBCD hexabromocyclododecane 
HCB hexachlorobenzene 
HCBD hexachlorobutadiene 
HCISHazardous Chemical Information System
HCT haematocrit
Health Australian Government Department of Health
hER human oestrogen receptor
HGPRThypoxanthine guanine phosphoribosyltransferase
HMW high molecular weight
HPLC high-performance liquid chromatography
HPV High Production Volume (chemicals)
hr hour
HSDB Hazardous Substances Data Bank
HSIS Hazardous Substances Information System
HVIC (Australian) High Volume Industrial Chemicals
Hydrate Hydrates are chemicals containing water of crystallisation—water molecules forming an essential part of the crystal structure of a compound—where the water does not react with the parent compound. Examples include hydrated copper sulfate (CuSO4.5H2O), cobalt chloride hexahydrate (CoCl2.6H2O) and asparagine monohydrate (C4H8N2O3H2O). The term hydrate is sometimes mistakenly attributed to chemicals where the water molecules have reacted with the parent compound, such as chloral hydrate (Cl3C-CH(OH)2) and ninhydrin, sometimes misleadingly called indane-1,2,3-trione monohydrate.
IARC International Agency for Research on Cancer
IC50 or IC50 half maximal inhibitory concentration
ICCA International Council of Chemical Associations
ICNA / IC(NA) Act Commonwealth Industrial Chemicals (Notification and Assessment) Act 1989
i.e. that is
IGHRC Interdepartmental Group on Health Risks from Chemicals
IMAP Inventory Multi-tiered Assessment and Prioritisation
INCHEMInternational Programme on Chemical Safety (also known as IPCS)
INCI International Nomenclature Cosmetic Ingredient Directory
Incidentally-produced chemical A chemical that is produced as a result of the:
  • exposure of another chemical to light, heat or other environmental conditions in the course of handling or storing, or
  • occurrence of a chemical reaction during the manufacture or use of another chemical (e.g. a by-product)
but not a chemical for which production has commercial value for a person manufacturing, handling, storing or using that other chemical.
Industry Australian Government Department of Industry
i.p. intraperitoneal
IPCS International Program on Chemical Safety (also known as INCHEM)
IRISIntegrated Risk Information System (US)
ISO International Organisation for Standardisation
iTE inherently toxic to the environment (Canada)
IUCLID International Uniform Chemical Information Database
i.v. intravenous
KOC organic carbon normalised adsorption coefficient
KOW or POW n-octanol/water partition coefficient
kg kilogram
KPI key performance indicator 
L litre
LC50 or LC50 median lethal concentration
LD50 or LD50 median lethal dose
LCLolowest published lethal concentration
LDLolowest published lethal dose
LH luteinising hormone
LLNAlocal lymph node assay
LMW low molecular weight
LOAEC lowest observed adverse effect concentration 
LOAEL lowest observed adverse effect level
LOD limit of detection
LOEC lowest observed effect concentration
LOEL lowest observed effect level
Log KOC Organic carbon coefficient
Log Kow or Kow  See Kow or Kow
Log Pow or Pow See Kow or Kow
LOQ limit of quantitation
LRCC low regulatory concern chemicals (NICNAS)
LTD Limited notification category for new chemicals (NICNAS)
LVC Low Volume Chemical permit for new chemicals (NICNAS)
LVCR Low Volume Chemical Permit Renewal for new chemicals (NICNAS)
MAK Maximum Workplace Concentration (translated)
MAN mutual acceptance of notification(s) (between countries)
m3 cubic metre
m–f male–female
mg/cm3milligrams per cubic centimetre
mg/kg bw/dmilligrams per kilogram bodyweight per day
μg microgram
μm micrometre
M molar (mol/L)
Manufacture Any process that involves a chemical reaction and results in the creation or synthesis of a chemical. Does not include blending.
MCH mean corpuscular (or cell) haemoglobin 
MCS Multiple Chemical Sensitivity 
MDD Maximum Daily Dose 
MEHP monoethylhexyl phthalate 
MEP monoethyl phthalate 
mg milligram
mg/cm³     milligrams per cubic centimetre 
mg/kg bw/d  milligram per kilogram bodyweight per day 
MIBP  monoisobutyl phthalate 
min minute
MITI Ministry of International Trade and Industry (Japan)
mL millilitre
Mm Micrometre
mM millimolar
mo month
MOE margin of exposure
mol mole
MOS margin of safety 
MOU memorandum of understanding 
mPa · s millipascal second
MRDD Maximum Recommended Daily Dose 
MRL maximum residue limit 
MS mass spectrometry
MSDS or SDS (Material) Safety Data Sheet
MW molecular weight
NAMW number-average molecular weight
NDSL Non Domestic Substances List (Canada) 
ng nanogram
NHANES National Health and Nutrition Examination Survey
NICNAS National Industrial Chemicals Notification and Assessment Scheme
NIOSHNational Institute for Occupational Safety and Health (US)
NOAEC no observed adverse effect concentration
NOAEL no observed adverse effect level
NOEC no observed effect concentration
NOEL no observed effect level
NOHSC National Occupational Health and Safety Commission—now called Safe Work Australia
NTP National Toxicology Program
OCS Office of Chemical Safety
ODP ozone depletion potential
OECD Organisation for Economic Co-operation and Development
OELoccupational exposure limit
OGTR Office of the Gene Technology Regulator 
P persistent
Pa pascal
PA phthalic acid 
PBDE polybrominated diphenylether 
PBFR polybrominated flame retardant 
PBS Portfolio Budget Statement 
PBT persistent, bioaccumulative and toxic (chemicals)
PCBUperson conducting a business or undertaking
PCBs  polychlorinated biphenyls 
PEC predicted environmental concentration; Priority Existing Chemical (NICNAS)
PELpermissible exposure limit
PFAS per- and poly-fluorinated alkyl substance
PFC perfluorinated chemicals 
PFCA perfluoroalkyl carboxylic acid 
PFOA perfluorooctanoic acid 
PFOS perfluorooctane sulfonate 
PFSAperfluoroalkyl sulfonate
PIC Prior Informed Consent (refers to Rotterdam Convention)
PLC Polymer of Low Concern category for new chemicals (NICNAS)
PND postnatal day
PNEC predicted no effect concentration
Polymer A substance consisting of molecules that:
  • are characterised by the sequence of one or more types of monomer units
  • are distributed over a range of molecular weights, and the differences in those molecular weights can be primarily attributed to differences in the number of monomer units
  • comprise a simple weight majority of molecules containing at least three monomer units covalently bound to at least one other monomer unit or other reactant, and
  • comprise less than a simple weight majority of molecules of the same molecular weight.
POP Persistent Organic Pollutant (refers to Stockholm Convention)
ppb parts per billion
ppbV parts per billion by volume
PPEpersonal protective equipment
ppm parts per million
ppmV parts per million by volume
Prescribed reactantIn relation to a polyester, means a substance listed as a prescribed reactant under Regulation 4AB of the Industrial Chemicals (Notification and Assessment) Regulations 1990.
PVC polyvinyl chloride
PVDC polyvinylidene chloride 
QSAR quantitative structure-activity relationship
Radioactive chemical a chemical having a specific activity greater than 35 becquerels per gram
RDD recommended daily dose
REACH The European Union's regulation for Registration, Evaluation, Authorisation and Restriction of Chemicals.
Reaction intermediate A substance that:
  • is produced in the course of a chemical reaction, and
  • has a transient existence, and
  • does not become a major component of the reaction mixture, and
  • is not removed from the reaction system.
Relevant industrial chemical For the purposes of NICNAS registration, an industrial chemical that is not intended for an excluded use and is not one of the following:
Research According to the ICNA Act, research does not include research for the purpose of determining market acceptance or consumer preferences.
RFG reactive functional group
risk probability or likelihood of harm and the likely extent of the harm; the probability of an adverse effect in an organism, system or (sub)population caused under specified circumstances by exposure to an agent
RQ risk quotient
s second
SA/BW surface area to body weight ratio
SANHC Self-assessment for Non-Hazardous Chemical notification for new chemicals (NICNAS)
SANHP Self-assessment for Non-Hazardous Polymer notification for new chemicals (NICNAS)
SAPLC Self-assessment for Polymer of Low Concern notification for new chemicals (NICNAS)
SAR structure-activity relationship
SCCNFP Scientific Committee on Cosmetic Products and Non-Food Products
SCCP Scientific Committee on Consumer Products
SCCS Scientific Committee on Consumer Safety
SD Sprague Dawley (rats)
SDS Safety Data Sheet
SIAM SIDS Initial Assessment Meeting (now CoCAM)
SIAP SIDS Initial Assessment Profile
SIAR SIDS Initial Assessment Report
SIDS Screening Information Data Set
SMILES Simplified Molecular Input Line Entry System
SOP standard operating procedure
SPIN Substances in Preparations In the Nordic countries
STD Standard notification category for new chemicals (NICNAS)
STEL short term exposure limits
STP sewage treatment plant
STVshort-term value
SUSMP Standard for the Uniform Scheduling of Medicines and Poisons
SVHC Substances of Very High Concern
SWA Safe Work Australia
Synthetic polymerAny polymer other than a biopolymer.
T toxic
t½ half life
TCLolowest published toxic concentration
TDLolowest published toxic dose
TEELtemporary emergency exposure limits
TG test guideline
TGA Therapeutic Goods Administration (Australia)
The Act Industrial Chemicals (Notification and Assessment) Act 1989 (Cwlth)
The Director Director of National Industrial Chemicals Notification and Assessment Scheme (NICNAS)
The Minister Minister for Health
TI tolerable intake
TLVthreshold limit values
TSCAToxic Substances Control Act (US EPA)
TWA time weighted average
UNUnited Nations
UNCED United Nations Conference on Environment and Development
UNEP United Nations Environment Program
US EPA United States Environmental Protection Agency
US FDA Food and Drug Administration (United States)
USA United States of America (also US)
USP United States Pharmacopoeia
UV ultra violet
UVCB (chemical of) Unknown or Variable Composition, complex reaction products or Biological material
vB very bioaccumulative
vP very persistent
vs versus, against
w/v weight to volume
w/w weight to weight
WHO World Health Organisation
WHSWork, Health and Safety
WPMN Working Party on Manufactured Nanomaterials
w/wweight per weight
yr year

Last update 5 April 2019